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Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature
BACKGROUND: Bone metastases represent a common and severe complication in breast cancer, and the involvement of cancer stem cells (CSCs) in the promotion of bone metastasis is currently under discussion. Here, we used a human-in-mice model to study bone metastasis formation due to primary breast CSC...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694250/ https://ncbi.nlm.nih.gov/pubmed/23801032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.271 |
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