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A novel mutation in the GCM2 gene causing severe congenital isolated hypoparathyroidism

OBJECTIVE: To investigate the GCM2 gene in three siblings with congenital hypoparathyroidism and perform functional analysis. MATERIALS AND METHODS: We sequenced the GCM2 gene by PCR and analyzed the functional consequence of the mutation by transient transfection studies. Haplotype analysis was per...

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Autors principals: Doyle, Daniel, Kirwin, Susan M., Sol-Church, Katia, Levine, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694175/
https://ncbi.nlm.nih.gov/pubmed/23155703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jpem-2012-0080
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