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Novel MicroRNA Reporter Uncovers Repression of Let-7 by GSK-3β

Several members of the let-7 microRNA family are downregulated in ovarian and other cancers. They are thought to act as tumor suppressors by lowering growth-promoting and anti-apoptotic proteins. In order to measure cellular let-7 levels systematically, we have developed a highly sensitive let-7 rep...

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Detalhes bibliográficos
Main Authors: Guo, Rong, Abdelmohsen, Kotb, Morin, Patrice J., Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694080/
https://ncbi.nlm.nih.gov/pubmed/23840442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066330
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