Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism

Cyclotides are a diverse and abundant group of ribosomally synthesized plant peptides containing a unique cyclic cystine-knotted topology that confers them with remarkable stability. Kalata B1, a representative member of this family of mini-proteins, has been found to inhibit the proliferation of hu...

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Detalhes bibliográficos
Main Authors: Gründemann, Carsten, Thell, Kathrin, Lengen, Karin, Garcia-Käufer, Manuel, Huang, Yen-Hua, Huber, Roman, Craik, David J., Schabbauer, Gernot, Gruber, Christian W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694003/
https://ncbi.nlm.nih.gov/pubmed/23840803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068016
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