Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest.

Transforming growth factor beta 1 (TGF beta 1) is a potent inhibitor of epithelial cell proliferation. We present data which indicate that epithelial cell proliferation is inhibited when TGF beta 1 is added throughout the prereplicative G1 phase. Cultures become reversibly blocked in late G1 at the...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Howe, P H, Draetta, G, Leof, E B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1996085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1185-1194.1991
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