The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells

BACKGROUND: Rhabdoid tumors are highly aggressive malignancies affecting infants and very young children. In many instances these tumors are resistant to conventional type chemotherapy necessitating alternative approaches. METHODS: Proliferation assays (MTT), apoptosis (propidium iodide/annexin V) a...

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Detalhes bibliográficos
Main Authors: Kerl, Kornelius, Ries, David, Unland, Rebecca, Borchert, Christiane, Moreno, Natalia, Hasselblatt, Martin, Jürgens, Heribert, Kool, Marcel, Görlich, Dennis, Eveslage, Maria, Jung, Manfred, Meisterernst, Michael, Frühwald, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693872/
https://ncbi.nlm.nih.gov/pubmed/23764045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-286
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