The Nrf2 Activator Oltipraz Also Activates the Constitutive Androstane Receptor

Oltipraz (OPZ) is a well known inducer of NAD(P)H:quinone oxidoreductase (NQO1) along with other enzymes that comprise the nuclear factor E2-related factor 2 (Nrf2) battery of detoxification genes. However, OPZ treatment also induces expression of CYP2B, a gene regulated by the constitutive androsta...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Merrell, Matthew D., Jackson, Jonathan P., Augustine, Lisa M., Fisher, Craig D., Slitt, Angela L., Maher, Jonathan M., Huang, Wendong, Moore, David D., Zhang, Youcai, Klaassen, Curtis D., Cherrington, Nathan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693743/
https://ncbi.nlm.nih.gov/pubmed/18474683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.020867
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi