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Disrupting the Scaffold to Improve Focal Adhesion Kinase–Targeted Cancer Therapeutics
Focal adhesion kinase (FAK) is emerging as a promising cancer target because it is highly expressed at both the transcriptional and translational level in cancer and is involved in many aspects of tumor growth, invasion, and metastasis. Existing FAK-based therapeutics focus on inhibiting the kinase&...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693475/ https://ncbi.nlm.nih.gov/pubmed/23532331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004021 |
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