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Metal ion determinants of conantokin dimerization as revealed in the X-ray crystallographic structure of the Cd(2+)/Mg(2+)–con-T[K7γ] complex

Predatory sea snails from the Conus family produce a variety of venomous small helical peptides called conantokins that are rich in γ-carboxyglutamic acid (Gla) residues. As potent and selective antagonists of the N-methyl-d-aspartate receptor, these peptides are potential therapeutic agents for a v...

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Hlavní autoři: Cnudde, Sara E., Prorok, Mary, Castellino, Francis J., Geiger, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693470/
https://ncbi.nlm.nih.gov/pubmed/20195692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-010-0633-2
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