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Development of novel tail-modified anandamide analogs
To explore the hydrophobic groove subsite within the CB1 cannabinoid receptor we have designed and synthesized a group of tail-substituted anandamide analogs. Our design involves the introduction of aryl or heterocyclic ring as terminal substituents that are connected to the last cis-arachidonyl dou...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693456/ https://ncbi.nlm.nih.gov/pubmed/18723350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.07.110 |
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