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Development of novel tail-modified anandamide analogs

To explore the hydrophobic groove subsite within the CB1 cannabinoid receptor we have designed and synthesized a group of tail-substituted anandamide analogs. Our design involves the introduction of aryl or heterocyclic ring as terminal substituents that are connected to the last cis-arachidonyl dou...

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Bibliografische gegevens
Hoofdauteurs: Yao, Fenmei, Li, Chen, Vadivel, Subramanian K, Bowman, Anna L, Makriyannis, Alexandros
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693456/
https://ncbi.nlm.nih.gov/pubmed/18723350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.07.110
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