Induced pluripotent stem cells with a pathological mitochondrial DNA deletion

In congenital mitochondrial DNA (mtDNA) disorders, a mixture of normal and mutated mtDNA (termed heteroplasmy) exists at varying levels in different tissues, which determines the severity and phenotypic expression of disease. Pearson marrow pancreas syndrome (PS) is a congenital bone marrow failure...

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Detalhes bibliográficos
Main Authors: Cherry, Anne B. C., Gagne, Katelyn E., McLoughlin, Erin M., Baccei, Anna, Gorman, Bryan, Hartung, Odelya, Miller, Justine D., Zhang, Jin, Zon, Rebecca L., Ince, Tan A., Neufeld, Ellis J., Lerou, Paul H., Fleming, Mark D., Daley, George Q., Agarwal, Suneet
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692613/
https://ncbi.nlm.nih.gov/pubmed/23400930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1354
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