Immunization Strategies To Block the Herpes Simplex Virus Type 1 Immunoglobulin G Fc Receptor

Herpes simplex virus type 1 (HSV-1) glycoprotein gE functions as an immunoglobulin G (IgG) Fc receptor (FcγR) that promotes immune evasion. When an IgG antibody binds by the F(ab′)(2) domain to an HSV antigen, the Fc domain of some of the same antibody molecules binds to the FcγR, which blocks Fc-me...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Lin, Xiaoqing, Lubinski, John M., Friedman, Harvey M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14963159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.5.2562-2571.2004
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