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Ablation of Keratan Sulfate Accelerates Early Phase Pathogenesis of ALS

Biopolymers consist of three major classes, i.e., polynucleotides (DNA, RNA), polypeptides (proteins) and polysaccharides (sugar chains). It is widely accepted that polynucleotides and polypeptides play fundamental roles in the pathogenesis of neurodegenerative diseases. But, sugar chains have been...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hirano, Kenichi, Ohgomori, Tomohiro, Kobayashi, Kazuyoshi, Tanaka, Fumiaki, Matsumoto, Tomohiro, Natori, Takamitsu, Matsuyama, Yukihiro, Uchimura, Kenji, Sakamoto, Kazuma, Takeuchi, Hideyuki, Hirakawa, Akihiro, Suzumura, Akio, Sobue, Gen, Ishiguro, Naoki, Imagama, Shiro, Kadomatsu, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692529/
https://ncbi.nlm.nih.gov/pubmed/23825599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066969
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