Highly Uneven Distribution of Tenofovir-Selected Simian Immunodeficiency Virus in Different Anatomical Sites of Rhesus Macaques

Antiviral tenofovir monotherapy was used to determine whether drug-selected simian immunodeficiency virus (SIV) variants replaced their wild-type progenitors at the same rate in different tissues of six rhesus macaques. The relative frequencies of drug-resistant and wild-type genotypes were measured...

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Detalhes bibliográficos
Main Authors: Magierowska, Magdalena, Bernardin, Flavien, Garg, Seema, Staprans, Silvija, Miller, Michael D., Van Rompay, Koen K. A., Delwart, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369237/
https://ncbi.nlm.nih.gov/pubmed/14963139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2434-2444.2004
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