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Divalent Metal Ion Triggered Activity of a Synthetic Antimicrobial in Cardiolipin Membranes

One member of a prototypical class of antimicrobial oligomers was used to study pore formation in cardiolipin rich membranes. Using both vesicle dye-leakage assays and small angle x-ray scattering, bilayer remodeling was studied. The results indicate that the presence of negative intrinsic curvature...

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Detalhes bibliográficos
Main Authors: Som, Abhigyan, Yang, Lihua, Wong, Gerard C. L., Tew, Gregory N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692289/
https://ncbi.nlm.nih.gov/pubmed/19807082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9067063
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