High throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses

We have developed a high throughput platform to detect the presence of HIV-1 and SIV-specific ADCC-mediating antibody responses. The assay is based on the hydrolysis of a cell-permeable fluorogenic peptide substrate containing a sequence recognized by the serine protease, Granzyme B (GzB). GzB is de...

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Hauptverfasser: Pollara, Justin, Hart, Lydia, Brewer, Faraha, Pickeral, Joy, Packard, Beverly, Hoxie, James A., Komoriya, Akira, Ochsenbauer, Christina, Kappes, John C., Roederer, Mario, Huang, Ying, Weinhold, Kent J., Tomaras, Georgia D., Haynes, Barton F., Montefiori, David C., Ferrari, Guido
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692008/
https://ncbi.nlm.nih.gov/pubmed/21735545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.21084
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