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Isolation of a simian virus 40 T-antigen-positive, transformation-resistant cell line by indirect selection.

In an attempt to identify cellular genes that might be involved in simian virus 40 (SV40) transformation, we have set out to isolate cells which express T antigen but are not transformed. SV40 DNA and the herpes simplex virus thymidine kinase gene were cotransfected into tk- 3T3 fibroblasts. Of 72 c...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Ryan, K W, Christensen, J B, Imperiale, M J, Brockman, W W
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1985
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369188/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3018524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.12.3577-3582.1985
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