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Simian virus 40 large T-antigen point mutants that are defective in viral DNA replication but competent in oncogenic transformation.

The large T antigen of simian virus 40 (SV40) is a multifunctional protein that is essential in both the virus lytic cycle and the oncogenic transformation of cells by SV40. To investigate the role of the numerous biochemical and physiological activities of T antigen in the lytic and transformation...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Manos, M M, Gluzman, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368881/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6330530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.6.1125-1133.1984
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