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Identifying Residues That Cause pH-dependent Reduction Potentials

The pH dependence of the reduction potential E° for a metalloprotein indicates that the protonation state of at least one residue near the redox site changes and may be important for its activity. The responsible residue is usually identified by site-specific mutagenesis, which may be time-consuming...

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Detalhes bibliográficos
Main Authors: Perrin, B. Scott, Ichiye, Toshiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691860/
https://ncbi.nlm.nih.gov/pubmed/23607577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4002858
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