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Impaired toll-like receptor 8 signaling in multiple sclerosis

BACKGROUND: The etiology and immunopathology of multiple sclerosis (MS) is not well understood. It is recognized that although autoreactive T cells are the main early mediators of disease, other cell types, including cells of the innate immune system contribute to MS pathogenesis. The objective of t...

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Main Authors: Johnson, Tory P, Tyagi, Richa, Patel, Karan, Schiess, Nicoline, Calabresi, Peter A, Nath, Avindra
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691740/
https://ncbi.nlm.nih.gov/pubmed/23787171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-74
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