IL-6 plays an obligatory role in late preconditioning via JAK–STAT signaling and upregulation of iNOS and COX-2

OBJECTIVE: We sought to determine whether interleukin (IL)-6 modulates myocardial infarction or the late phase of preconditioning (PC). METHODS: Wild-type and IL-6(−/−) mice underwent a 30-min coronary occlusion followed by 24 h of reperfusion with or without six cycles of coronary occlusion/reperfu...

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Detalhes bibliográficos
Main Authors: Dawn, Buddhadeb, Xuan, Yu-Ting, Guo, Yiru, Rezazadeh, Arash, Stein, Adam B., Hunt, Greg, Wu, Wen-Jian, Tan, Wei, Bolli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691700/
https://ncbi.nlm.nih.gov/pubmed/15364614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2004.05.011
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