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Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression
BACKGROUND: Ciliary neurotrophic factor (CNTF) expression is repressed in astrocytes by neuronal contact in the CNS and is rapidly induced by injury. Here, we defined an inhibitory integrin signaling pathway. RESULTS: The integrin substrates laminin, fibronectin and vitronectin, but not collagen, th...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691611/ https://ncbi.nlm.nih.gov/pubmed/23693126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-35 |
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