載入...
The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase
DNA replication depends on a preceding licensing event by Cdt1 and Cdc6. In animal cells, relicensing after S phase but before mitosis is prevented by the Cdt1 inhibitor geminin and mitotic cyclin activity. Here, we show that geminin, like cyclin B1 and securin, is a bona fide target of the spindle...
Na minha lista:
| Main Authors: | , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2013
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691463/ https://ncbi.nlm.nih.gov/pubmed/23775192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201211019 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|