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The Disease Ameliorating Function of Autoregulatory CD8 T-cells Is Mediated by Targeting of Encephalitogenic CD4 T-cells in EAE
Multiple Sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) and CD8 T-cells are the predominant T-cell population in MS lesions. Given that transfer of CNS-specific CD8 T-cells results in an attenuated clinical demyelinating disease in C57BL/6 mice with im...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691355/ https://ncbi.nlm.nih.gov/pubmed/23733879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300452 |
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