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The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity

Translocations occur through the aberrant joining of large stretches of non-contiguous chromosomal regions. The substrates for these illegitimate rearrangements can arise as a result of damage incurred during normal cellular processes, such as transcription and replication, or through the action of...

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Autores principales: Rocha, Pedro P., Skok, Jane A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691303/
https://ncbi.nlm.nih.gov/pubmed/23478218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2013.02.007
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