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Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy

PURPOSE: Clinicopathologic features and biochemical recurrence are sensitive, but not specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a genomic expression signature detected in the primary tumor represents true biological potential of aggressive disease and...

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Detalhes bibliográficos
Main Authors: Erho, Nicholas, Crisan, Anamaria, Vergara, Ismael A., Mitra, Anirban P., Ghadessi, Mercedeh, Buerki, Christine, Bergstralh, Eric J., Kollmeyer, Thomas, Fink, Stephanie, Haddad, Zaid, Zimmermann, Benedikt, Sierocinski, Thomas, Ballman, Karla V., Triche, Timothy J., Black, Peter C., Karnes, R. Jeffrey, Klee, George, Davicioni, Elai, Jenkins, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691249/
https://ncbi.nlm.nih.gov/pubmed/23826159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066855
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