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Regional Differences in Islet Distribution in the Human Pancreas - Preferential Beta-Cell Loss in the Head Region in Patients with Type 2 Diabetes

While regional heterogeneity in islet distribution has been well studied in rodents, less is known about human pancreatic histology. To fill gaps in our understanding, regional differences in the adult human pancreas were quantitatively analyzed including the pathogenesis of type 2 diabetes (T2D). C...

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Detalhes bibliográficos
Main Authors: Wang, Xiaojun, Misawa, Ryosuke, Zielinski, Mark C., Cowen, Peter, Jo, Junghyo, Periwal, Vipul, Ricordi, Camillo, Khan, Aisha, Szust, Joel, Shen, Junhui, Millis, J. Michael, Witkowski, Piotr, Hara, Manami
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691162/
https://ncbi.nlm.nih.gov/pubmed/23826303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067454
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