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Altered Islet Composition and Disproportionate Loss of Large Islets in Patients with Type 2 Diabetes

Human islets exhibit distinct islet architecture with intermingled alpha- and beta-cells particularly in large islets. In this study, we quantitatively examined pathological changes of the pancreas in patients with type 2 diabetes (T2D). Specifically, we tested a hypothesis that changes in endocrine...

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Detalhes bibliográficos
Main Authors: Kilimnik, German, Zhao, Billy, Jo, Junghyo, Periwal, Vipul, Witkowski, Piotr, Misawa, Ryosuke, Hara, Manami
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216964/
https://ncbi.nlm.nih.gov/pubmed/22102895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027445
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