Poliovirus mutant that does not selectively inhibit host cell protein synthesis.

A poliovirus type I (Mahoney strain) mutant was obtained by inserting three base pairs into an infectious cDNA clone. The extra amino acid encoded by the insertion was in the amino-terminal (protein 8) portion of the P2 segment of the polyprotein. The mutant virus makes small plaques on HeLa and mon...

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Bibliographic Details
Main Authors: Bernstein, H D, Sonenberg, N, Baltimore, D
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC369102/
https://ncbi.nlm.nih.gov/pubmed/3018486
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