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Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepuberty

Developmental stage of rat mammary gland at the time of estrogen exposure determines whether the exposure increases or reduces later breast cancer risk. For example, in utero exposure to 17β-estradiol (E2) increases, whereas prepubertal exposure to this hormone decreases susceptibility of developing...

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Autori principali: Shajahan, Ayesha N., Goel, Shruti, de Assis, Sonia, Yu, Bin, Clarke, Robert, Hilakivi-Clarke, Leena
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690959/
https://ncbi.nlm.nih.gov/pubmed/23805170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hmbci.2010.031
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