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Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model

Background: Responses to endocrine therapies vary among patients with estrogen receptor (ER+) breast cancer. We studied whether in utero exposure to endocrine-disrupting compounds might explain these variations. Methods: We describe a novel ER+ breast cancer model to study de novo and acquired tamox...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Hilakivi-Clarke, Leena, Wärri, Anni, Bouker, Kerrie B, Zhang, Xiyuan, Cook, Katherine L, Jin, Lu, Zwart, Alan, Nguyen, Nguyen, Hu, Rong, Cruz, M Idalia, de Assis, Sonia, Wang, Xiao, Xuan, Jason, Wang, Yue, Wehrenberg, Bryan, Clarke, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255695/
https://ncbi.nlm.nih.gov/pubmed/27609189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw188
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