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Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry

Rotavirus (RV) is the major cause of childhood gastroenteritis worldwide. This study presents a functional genome-scale analysis of cellular proteins and pathways relevant for RV infection using RNAi. Among the 522 proteins selected in the screen for their ability to affect viral infectivity, an enr...

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Detalhes bibliográficos
Main Authors: Silva-Ayala, Daniela, López, Tomás, Gutiérrez, Michelle, Perrimon, Norbert, López, Susana, Arias, Carlos F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690850/
https://ncbi.nlm.nih.gov/pubmed/23733942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304932110
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