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A Genome-Wide RNAi Screen Identifies Core Components of the G(2)-M DNA Damage Checkpoint

The DNA damage checkpoint, the first pathway known to be activated in response to DNA damage, is a mechanism by which the cell cycle is temporarily arrested to allow DNA repair. The checkpoint pathway transmits signals from the sites of DNA damage to the cell cycle machinery through the evolutionari...

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Detalhes bibliográficos
Main Authors: Kondo, Shu, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489265/
https://ncbi.nlm.nih.gov/pubmed/21205937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001350
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