Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype

Although a large number of actin-binding proteins and their regulators have been identified through classical approaches, gaps in our knowledge remain. Here, we used genome-wide RNA interference as a systematic method to define metazoan actin regulators based on visual phenotype. Using comparative s...

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Detalhes bibliográficos
Main Authors: Rohn, Jennifer L., Sims, David, Liu, Tao, Fedorova, Marina, Schöck, Frieder, Dopie, Joseph, Vartiainen, Maria K., Kiger, Amy A., Perrimon, Norbert, Baum, Buzz
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171124/
https://ncbi.nlm.nih.gov/pubmed/21893601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103168
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