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Comparative Proteomic Analysis Identifies Age-Dependent Increases in the Abundance of Specific Proteins after Deletion of the Small Heat Shock Proteins αA- and αB-Crystallin
Mice with deletion of genes for small heat shock proteins αA- and αB-crystallin (αA/αB(−/−)) develop cataracts. We used proteomic analysis to identify lens proteins that change in abundance after deletion of these α-crystallin genes. Wild-type (WT) and αA/αB(−/−) knockout (DKO) mice were compared us...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690595/ https://ncbi.nlm.nih.gov/pubmed/23590631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400180d |
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