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Increased CD8(+) T-cell Function following Castration and Immunization Is Countered by Parallel Expansion of Regulatory T Cells

Although androgen ablation therapy is effective in treating primary prostate cancers, a significant number of patients develop incurable castration-resistant disease. Recent studies have suggested a potential synergy between vaccination and androgen ablation, yet the enhanced T-cell function is tran...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Tang, Shuai, Moore, Miranda L., Grayson, Jason M., Dubey, Purnima
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690568/
https://ncbi.nlm.nih.gov/pubmed/22374980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2499
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