APOBEC3B Deletion and Risk of HIV-1 Acquisition

The human APOBEC3 family of cytidine deaminases provides intrinsic immunity to retroviral infection. A naturally occurring 29.5-kb deletion removes the entire APOBEC3B gene. We examined the impact of the APOBEC3B gene deletion in >4000 individuals from five HIV-1 natural history cohorts. The hemi...

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Main Authors: An, Ping, Johnson, Randall, Phair, John, Kirk, Gregory D., Yu, Xiao-Fang, Donfield, Sharyne, Buchbinder, Susan, Goedert, James J., Winkler, Cheryl A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690486/
https://ncbi.nlm.nih.gov/pubmed/19698078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/605644
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