Error-prone mutagenesis detected in mammalian cells by a shuttle vector containing the supF gene of Escherichia coli.
When a shuttle vector containing a tyrosine suppressor tRNA (supF) gene as a target for mutagenesis replicated in a monkey kidney cell line, the frequency of SupF+ mutations was 2.3 +/- 0.5 x 10(-3). When the host cells were treated with ethyl methanesulfonate 40 h before transfection, a 10-fold inc...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1984
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6095049/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.10.2227-2230.1984 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|