Error-prone mutagenesis detected in mammalian cells by a shuttle vector containing the supF gene of Escherichia coli.

When a shuttle vector containing a tyrosine suppressor tRNA (supF) gene as a target for mutagenesis replicated in a monkey kidney cell line, the frequency of SupF+ mutations was 2.3 +/- 0.5 x 10(-3). When the host cells were treated with ethyl methanesulfonate 40 h before transfection, a 10-fold inc...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Sarkar, S, Dasgupta, U B, Summers, W C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1984
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6095049/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.10.2227-2230.1984
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