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Cold-induced RNA-binding proteins regulate circadian gene expression by controlling alternative polyadenylation

The body temperature is considered a universal cue by which the master clock synchronizes the peripheral clocks in mammals, but the mechanism is not fully understood. Here we identified two cold-induced RNA-binding proteins (RBPs), Cirbp and Rbm3, as important regulators for the temperature entraine...

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Detalhes bibliográficos
Main Authors: Liu, Yuting, Hu, Wenchao, Murakawa, Yasuhiro, Yin, Jingwen, Wang, Gang, Landthaler, Markus, Yan, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690385/
https://ncbi.nlm.nih.gov/pubmed/23792593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02054
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