Autocrine Transforming Growth Factor-β1 Promotes in vivo Th17 Cell Differentiation

TGFβ1 is a regulatory cytokine that has an important role in controlling T cell differentiation. T cell-produced TGFβ1 acts on T cells to promote Th17 cell differentiation and the development of experimental autoimmune encephalomyelitis (EAE). However, the exact TGFβ1-producing T cell subset require...

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Main Authors: Gutcher, Ilona, Donkor, Moses K., Ma, Qian, Rudensky, Alexander Y., Flavell, Richard A., Li, Ming O.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690311/
https://ncbi.nlm.nih.gov/pubmed/21435587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.03.005
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