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Antidepressant Treatment Reduces Serotonin-1A Autoreceptor Binding in Major Depressive Disorder
BACKGROUND: Chronic selective serotonin reuptake inhibitor (SSRI) administration to rodents desensitizes or downregulates raphe 5-HT(1A) autoreceptors. We previously found elevated 5-HT(1A) binding in antidepressant-naïve and not recently-medicated major depressive disorder, and now report the effec...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690146/ https://ncbi.nlm.nih.gov/pubmed/23374637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.11.012 |
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