A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction

AIM: To compare plasma 4β-hydroxycholesterol : cholesterol with urinary 6β-hydroxycortisol : cortisol as markers of cytochrome P4503A4 activity before and after treatment with rifampicin for 2 weeks. METHOD: 6β-hydroxycortisol and cortisol were determined by liquid chromatography tandem mass spectro...

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Библиографические подробности
Главные авторы: Mårde Arrhén, Yvonne, Nylén, Hanna, Lövgren-Sandblom, Anita, Kanebratt, Kajsa P, Wide, Katarina, Diczfalusy, Ulf
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2013
Предметы:
Methods in Clinical Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690112/
https://ncbi.nlm.nih.gov/pubmed/23116409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12016
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