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Conformational determinants of the activity of Antiproliferative factor glycopeptide

The antiproliferative factor (APF) involved in interstitial cystitis is a glycosylated nonapeptide (TVPAAVVVA) containing a sialylated core α-O-disaccharide linked to the N-terminal threonine. The chemical structure of APF was deduced using spectroscopic techniques and confirmed using total synthesi...

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Detalhes bibliográficos
Main Authors: Mallajosyula, Sairam S., Adams, Kristie M., Barchi, Joseph J., MacKerell, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690088/
https://ncbi.nlm.nih.gov/pubmed/23627670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci400147s
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