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Hsp70 Targets a Cytoplasmic Quality Control Substrate to the San1p Ubiquitin Ligase

Accumulation of misfolded proteins in cellular compartments can result in stress-induced cell death. In the endoplasmic reticulum (ER), ER-associated degradation clears aberrant proteins from the secretory pathway. In the cytoplasm and nucleus, this job is left to the cytoplasmic quality control (Cy...

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Библиографические подробности
Главные авторы: Guerriero, Christopher J., Weiberth, Kurt F., Brodsky, Jeffrey L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689992/
https://ncbi.nlm.nih.gov/pubmed/23653356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475905
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