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Hepatitis B Viral RNA Directly Mediates Down-regulation of the Tumor Suppressor MicroRNA miR-15a/miR-16-1 in Hepatocytes

Hepatitis B virus (HBV) is a key risk factor for the development of hepatocellular carcinoma (HCC). Recent work suggests a functional link between HCC and microRNA expression, but the mechanism underlying the functional interaction between microRNA and HBV infection has remained largely elusive. Her...

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Detalhes bibliográficos
Main Authors: Wang, Yanling, Jiang, Li, Ji, Xiong, Yang, Bo, Zhang, Yi, Fu, Xiang-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689990/
https://ncbi.nlm.nih.gov/pubmed/23649629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458158
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