The Universal Epitope of Influenza A Viral Neuraminidase Fundamentally Contributes to Enzyme Activity and Viral Replication

The only universally conserved sequence among all influenza A viral neuraminidases is located between amino acids 222 and 230. However, the potential roles of these amino acids remain largely unknown. Through an array of experimental approaches including mutagenesis, reverse genetics, and growth kin...

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Bibliographische Detailangaben
Hauptverfasser: Doyle, Tracey M., Jaentschke, Bozena, Van Domselaar, Gary, Hashem, Anwar M., Farnsworth, Aaron, Forbes, Nicole E., Li, Changgui, Wang, Junzhi, He, Runtao, Brown, Earl G., Li, Xuguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689970/
https://ncbi.nlm.nih.gov/pubmed/23645684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468884
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