The Universal Epitope of Influenza A Viral Neuraminidase Fundamentally Contributes to Enzyme Activity and Viral Replication

The only universally conserved sequence among all influenza A viral neuraminidases is located between amino acids 222 and 230. However, the potential roles of these amino acids remain largely unknown. Through an array of experimental approaches including mutagenesis, reverse genetics, and growth kin...

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Autors principals: Doyle, Tracey M., Jaentschke, Bozena, Van Domselaar, Gary, Hashem, Anwar M., Farnsworth, Aaron, Forbes, Nicole E., Li, Changgui, Wang, Junzhi, He, Runtao, Brown, Earl G., Li, Xuguang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689970/
https://ncbi.nlm.nih.gov/pubmed/23645684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468884
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