The Universal Epitope of Influenza A Viral Neuraminidase Fundamentally Contributes to Enzyme Activity and Viral Replication

The only universally conserved sequence among all influenza A viral neuraminidases is located between amino acids 222 and 230. However, the potential roles of these amino acids remain largely unknown. Through an array of experimental approaches including mutagenesis, reverse genetics, and growth kin...

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Detalhes bibliográficos
Main Authors: Doyle, Tracey M., Jaentschke, Bozena, Van Domselaar, Gary, Hashem, Anwar M., Farnsworth, Aaron, Forbes, Nicole E., Li, Changgui, Wang, Junzhi, He, Runtao, Brown, Earl G., Li, Xuguang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689970/
https://ncbi.nlm.nih.gov/pubmed/23645684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468884
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