Notch1 Gene Mutations Target KRAS G12D-expressing CD8(+) Cells and Contribute to Their Leukemogenic Transformation

Acute T-cell lymphoblastic leukemia/lymphoma (T-ALL) is an aggressive hematopoietic malignancy affecting both children and adults. Previous studies of T-ALL mouse models induced by different genetic mutations have provided highly diverse results on the issues of T-cell leukemia/lymphoma-initiating c...

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Hlavní autoři: Kong, Guangyao, Du, Juan, Liu, Yangang, Meline, Benjamin, Chang, Yuan-I, Ranheim, Erik A., Wang, Jinyong, Zhang, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689964/
https://ncbi.nlm.nih.gov/pubmed/23673656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475376
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